[HTML][HTML] Homocitrullination is a novel histone H1 epigenetic mark dependent on aryl hydrocarbon receptor recruitment of carbamoyl phosphate synthase 1
AD Joshi, MG Mustafa, CF Lichti, CJ Elferink - Journal of Biological …, 2015 - ASBMB
The aryl hydrocarbon receptor (AhR), a regulator of xenobiotic toxicity, is a member of the
eukaryotic Per-Arnt-Sim domain protein family of transcription factors. Recent evidence
identified a novel AhR DNA recognition sequence called the nonconsensus xenobiotic
response element (NC-XRE). AhR binding to the NC-XRE in response to activation by the
canonical ligand 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin resulted in concomitant recruitment of
carbamoyl phosphate synthase 1 (CPS1) to the NC-XRE. Studies presented here …
eukaryotic Per-Arnt-Sim domain protein family of transcription factors. Recent evidence
identified a novel AhR DNA recognition sequence called the nonconsensus xenobiotic
response element (NC-XRE). AhR binding to the NC-XRE in response to activation by the
canonical ligand 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin resulted in concomitant recruitment of
carbamoyl phosphate synthase 1 (CPS1) to the NC-XRE. Studies presented here …
